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Immune Support

Immune Support is the state-of-the-art Aloe Vera inner leaf gel power containing the industry’s highest standardized levels of Aloe Vera’s most bio-active ingredient called Acemannan. Immune Support, developed specifically for MannaRelief as an advanced technology, contains the industry’s highest levels of Acemannan and it’s most beneficial fractions.

Advanced Aloe Technology for Immune Modulation Support

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Immune Support is organic Aloe Vera
Inner Leaf Gel Freeze Dried Powder

  • HIGHEST Total Acemannan
  • HIGHEST Immunomodulatory Acemannan < 400 kDa
  • HIGHEST Bio-available Acemannan < 50 kDa
  • FULL SPECTRUM of Molecular Weight Polysaccharides
  • Aloin Free (< 0.00142%)
  • Completely Water Soluble


Over 70 percent of the body’s immune cells are located in the gut. Acemannan must be the correct size to be detected and engulfed by macrophages. Macrophages, essential immune cells, act as directors of various immune responses. Studies have shown that Acemannans with a molecular weight of < 400 kDa are powerful macrophage activators while those larger than 400 kDa have only a marginal immunomodulatory activity. Activated macrophages are deeply involved in self-regulated immunomodulation.


Acemannans with a molecular weight of less than 50 kDa can be absorbed immediately through the intestinal walls and transported into the blood stream. The role of mannose is so important to our overall health and immune function that epithelial cells lining the gut have mannose-specific receptors for the active uptake of these manose structures from our diets. Once absorbed, they are transported directly in to the blood stream and delivered to other cells, tissues, and organs throughout the body. Mannose is essential for all cellular functions,
including those involved in repair, regeneration, and defense.

Integrative Health

Immune Support combines the best standards of care with the best technology to achieve best patient outcomes.

*Materials and MethodsSamplesImmune Support, C, P, and A were ranked based upon their respective Total Acemannan. Numerous “other” samples were tested; however, they did not qualify for inclusion in the graph because they lack the full range of immunomodulatory Acemannan. For each sample listed, the Total acemannan was calculated using the “o-acetyl method” then checked against the SEC (Size Exclusion Chromatography) for accuracy using the total polysaccharides as the marker. The SEC data was also used to determine the < 50 kDa and < 400 kDa Fractions. Both tests were performed by different independant laboratories using blind samples.

Other Ingredients: Sunflower lecithin, white rice flour, vegetable capsules.
Our vegetable capsules are made from 100% non-animal material.

Recommended Use: Take one capsule one time daily with 8 fl oz of water or juice.

Warning: If you are pregnant, nursing, taking medications, or planning a medical procedure, consult your health professional before use. Discontinue use and consult a doctor if any adverse reactions occur. Do not use if the inner seal is missing or broken. Keep out of reach of children. Keep bottle tightly closed. Store in a cool, dry place.

Manufactured exclusively for MannaRelief: PO Box 540669 Grand Prairie, TX 75054 USA

This product is not intended to diagnose, treat, cure, or prevent any disease