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The IMPACT 500 Immune Support Program

For each donation of $89.00, 17 children will receive a full month supply of advanced immune support and you will receive a complimentary bottle of advanced immune support for you or a member of your family.

What is the Impact 500 Program
What is Acemannan?

Join the Mission to Bless God’s Children
with Advanced Immune Nutritional Support!

Each year, 7 million children die from Immune Deficiency related diseases.
That’s one child every 4.5 seconds!


servings of nutrition*

Integrative Health Support

MannaRelief is a nonprofit organization that has been giving the exclusive rights to nature’s most powerful immune optimizing nutritional extract called Acemannan.

In areas of the world where modern healthcare is not accessible, turning on a child’s immune system can be the difference between life and death.

Our nutritional support products are designed to work synergistically with standard of care medical therapies in order to achieve best patient outcomes.

Meet Sam Caster
Co-founder of MannaRelief

Sam Caster - Manna Relief Project

How to Change the World

(click the cover to read)


In 1997, Sam and Linda Caster provided the world’s first stabilized Acemannan extract to an orphanage organization in Romania. The children in those orphanages suffered from a plethora of chronic and infectious conditions, resulting in 30 to 40 deaths per year. 

The quality of life of these children was dramatically improved and for the first time in over a decade, not one child died that year in their organization. These results triggered the founding of MannaRelief in January 1999. MannaRelief was then granted exclusive rights to Acemannan for global relief distribution. 

Global Reach - Established distribution

MannaRelief started with one orphanage in Romania. Eleven years later with thousands of people around the world joining together, we’re addressing the problem of malnutrition for children everywhere.